Cheap Flights from San Diego International to St Louis

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Flight deals from San Diego International to St Louis

Looking for a cheap last-minute deal or the best return flight from San Diego International to St Louis? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from San Diego International to St Louis

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like San Diego International to St Louis flights are currently cheapest in April.

Direct flights from San Diego International to St Louis

San Diego International to St Louis: Alternative routes

Compare routes from San Diego International to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

San Diego to St Louis: Flight information

The things to know before you go.
Cheapest flight found$303
Cheapest month to flyApril
Average flight time3 hrs, 38 mins
Most popular airlineSouthwest Airlines
Average flights per week11

Finding cheap flights from San Diego International to St Louis: Frequently asked questions

The best price we found for a return flight from San Diego International to St Louis is $303. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
3 hours and 38 minutes is the average flight time from San Diego International to St Louis.
Southwest Airlines and Sun Country Airlines fly direct from San Diego International to St Louis.
As of April 2025, there are 11 flights per week flying from San Diego International to St Louis.
The cheapest month to fly from San Diego International to St Louis is usually April 2025.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from San Diego International Airport to St Louis Airport on Thursday, 24 April 2025.
Yes – the average flight time is 3 hours and 38 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Frontier Airlines and Southwest Airlines offer the cheapest flight tickets to St Louis.

Travelling from San Diego International Airport (SAN) to Lambert-St. Louis International Airport (STL): what you need to know

  • Around 3 hours 30 minutes is how long you'll be travelling on a direct flight from San Diego International Airport to Lambert-St. Louis International Airport.

  • The timezone in St Louis is UTC-5, which is two hours ahead of San Diego.

  • You can choose from eight weekly San Diego International Airport to Lambert-St. Louis International Airport flights. The 06:25 departure with Southwest Airlines is the earliest flight available. Southwest Airlines operates the latest service of the day at 18:55.

  • Leave plenty of time to catch your SAN to STL flight. It's generally best to arrive at least two hours before international departures and an hour ahead for domestic flights.

  • You'll likely experience longer queues during popular months like July. Arriving up to four hours in advance for international flights and two hours for a domestic departure will give you ample time for security and boarding.

  • Southwest Airlines is your ticket to exploring St Louis (and perhaps some other exciting parts of United States!). Check out the direct flights from San Diego International Airport to Lambert-St. Louis International Airport offered by this popular carrier.

  • Most travellers choose to fly with Southwest Airlines on this route.

  • Among carriers operating SAN to STL flights, Southwest Airlines has the best track record for timely arrivals.

  • Think about adding a stopover when booking your ticket from San Diego International Airport to Lambert-St. Louis International Airport. Simply deselect 'Direct flights only' to break up your trip, or perhaps explore a new destination along the way. Here are some options between SAN and STL:

    • Phoenix Sky Harbour International Airport

    • Denver International Airport

    • Harry Reid Airport (formerly McCarran Airport)

How to find the cheapest flights from San Diego International Airport (SAN) to Lambert-St. Louis International Airport (STL)

  • Right now, $161 is the cheapest price we've seen for a one-way San Diego International Airport to Lambert-St. Louis International Airport flight. The best price for a return ticket is $303. Bear in mind that fares could change due to demand when booking.

  • To pick up cheap tickets from SAN to STL, book your trip six months ahead of your departure.

  • May is the cheapest month for flights from San Diego International Airport to Lambert-St. Louis International Airport. If you want to travel during a different time of year, the 'Whole month' tool will give you the lowest prices across every month.

  • Landing cheap flights from SAN to STL is a breeze with Price Alerts. Simply create one of these automatic alerts and we'll notify you when there's a better deal.

  • Tailor your flights using filters. Select your departure and arrival times, total journey duration and airlines. You can also sort your results by 'Best,' 'Fastest' or 'Cheapest' flights from San Diego International Airport to Lambert-St. Louis International Airport.

Handy information about San Diego International Airport (SAN)

  • SAN's address is Airport Drive.

  • Of the flights that depart from San Diego International Airport, 71.38% land on time at their destination.

  • Central San Diego to San Diego International Airport is around 5 kilometres. Depending on traffic, it'll take you about 10 minutes to get there if you're catching a cab, ride-sharing or driving.

  • You can expect a journey time of about 20 minutes when using public transport.

  • Get your trip off to a hassle-free start by staying near SAN. Whether you're catching an early flight from San Diego International Airport to Lambert-St. Louis International Airport or just don't want to be rushed, these stays are perfect:

Arriving at Lambert-St. Louis International Airport (STL)

Getting from Lambert-St. Louis International Airport (STL) to central St Louis

  • STL is located at 10701 Lambert International Blvd..

  • Lambert-St. Louis International Airport to the centre of St Louis has a drive time of about 20 minutes. It's approximately 26 kilometres away.

  • Getting to the centre by public transport typically takes 35 minutes.

When to fly to Lambert-St. Louis International Airport (STL)

  • July is the busiest month for flights from San Diego International Airport to Lambert-St. Louis International Airport. To skip the crowds, visit St Louis in April.

  • The warmest month in St Louis is July, with temperatures ranging between 17ºC and 33ºC. Lock in your flights from San Diego International Airport to Lambert-St. Louis International Airport in this month if you enjoy this type of weather.

  • January has average temperatures of between -8ºC and 7ºC. Look for cheap tickets from SAN to STL sometime around then if you want to travel when it's cooler.

Explore more of United States

  • Chicago is just one of the many places in United States waiting to be discovered once you've seen the sights of St Louis. Around 418 kilometres away to the north-east, its best attractions include Millennium Park, Art Institute of Chicago and LandShark Beer Garden at Navy Pier.

  • If there's time to check out another well-known destination in United States, consider Indianapolis, roughly 370 kilometres east of St Louis. The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo are highlights.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.