Cheap Flights from Manaus to Panama City from $714

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Find the cheapest month or even day of the year to fly to Panama City

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Flight deals from Manaus Airport to Panama City

Looking for a cheap last-minute deal or the best return flight from Manaus Airport to Panama City? If you want to travel next month, return fares start from $776. Find the lowest prices on one-way and return tickets right here.

Panama City.$714 per passenger.Departing Thu, 26 Mar, returning Fri, 27 Mar.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Thu, 26 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 27 Mar, arriving in Manaus.Price includes taxes and charges.From $714, select.

Panama City.$714 per passenger.Departing Mon, 22 Jun, returning Mon, 29 Jun.Return flight with GOL Linhas Aéreas and Avianca.Outbound indirect flight with GOL Linhas Aéreas, departs from Manaus on Mon, 22 Jun, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 29 Jun, arriving in Manaus.Price includes taxes and charges.From $714, select.

Panama City.$716 per passenger.Departing Sat, 12 Sep, returning Mon, 21 Sep.Return flight with GOL Linhas Aéreas and Avianca.Outbound indirect flight with GOL Linhas Aéreas, departs from Manaus on Sat, 12 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 21 Sep, arriving in Manaus.Price includes taxes and charges.From $716, select.

Panama City.$716 per passenger.Departing Thu, 28 May, returning Sun, 7 Jun.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Thu, 28 May, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 7 Jun, arriving in Manaus.Price includes taxes and charges.From $716, select.

Panama City.$721 per passenger.Departing Mon, 30 Mar, returning Wed, 1 Apr.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Mon, 30 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 1 Apr, arriving in Manaus.Price includes taxes and charges.From $721, select.

Panama City.$754 per passenger.Departing Thu, 16 Jul, returning Wed, 22 Jul.Return flight with GOL Linhas Aéreas and Avianca.Outbound indirect flight with GOL Linhas Aéreas, departs from Manaus on Thu, 16 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 22 Jul, arriving in Manaus.Price includes taxes and charges.From $754, select.

Panama City.$776 per passenger.Departing Thu, 10 Sep, returning Thu, 17 Sep.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Thu, 10 Sep, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Thu, 17 Sep, arriving in Manaus.Price includes taxes and charges.From $776, select.

Panama City.$776 per passenger.Departing Tue, 21 Apr, returning Tue, 28 Apr.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Tue, 21 Apr, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Tue, 28 Apr, arriving in Manaus.Price includes taxes and charges.From $776, select.

Panama City.$776 per passenger.Departing Mon, 1 Jun, returning Thu, 4 Jun.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Mon, 1 Jun, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Thu, 4 Jun, arriving in Manaus.Price includes taxes and charges.From $776, select.

Panama City.$776 per passenger.Departing Fri, 27 Nov, returning Mon, 7 Dec.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Fri, 27 Nov, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 7 Dec, arriving in Manaus.Price includes taxes and charges.From $776, select.

Panama City.$776 per passenger.Departing Fri, 1 May, returning Sun, 10 May.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Fri, 1 May, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 10 May, arriving in Manaus.Price includes taxes and charges.From $776, select.

Panama City.$776 per passenger.Departing Thu, 28 May, returning Sun, 7 Jun.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Thu, 28 May, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 7 Jun, arriving in Manaus.Price includes taxes and charges.From $776, select.

Panama City.$776 per passenger.Departing Thu, 1 Oct, returning Mon, 5 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Thu, 1 Oct, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 5 Oct, arriving in Manaus.Price includes taxes and charges.From $776, select.

Panama City.$777 per passenger.Departing Tue, 21 Jul, returning Sun, 26 Jul.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Tue, 21 Jul, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 26 Jul, arriving in Manaus.Price includes taxes and charges.From $777, select.

Panama City.$777 per passenger.Departing Fri, 23 Oct, returning Sun, 1 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Fri, 23 Oct, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 1 Nov, arriving in Manaus.Price includes taxes and charges.From $777, select.

Panama City.$777 per passenger.Departing Thu, 30 Apr, returning Sun, 3 May.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Thu, 30 Apr, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 3 May, arriving in Manaus.Price includes taxes and charges.From $777, select.

Find the cheapest month to fly from Manaus to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Manaus to Panama City flights are currently cheapest in March.

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Direct flights from Manaus to Panama City

Alternative Manaus to Panama City routes

Looking for the cheapest, fastest or easiest route from Manaus to Panama City? You could fly into the following airports instead.

Manaus to Panama City: Flight information

The things to know before you go.

Cheapest flight found	$714
Cheapest month to fly	March
Average flight time	3 hrs, 46 mins
Most popular airline	Copa
Average flights per week	50

Finding cheap flights from Manaus to Panama City: Frequently asked questions

How many airports are there in Panama City?

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.

How much are return flights from Manaus to Panama City?

The best price we found for a return flight from Manaus to Panama City is $714. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Manaus to Panama City?

3 hours and 46 minutes is the average flight time from Manaus to Panama City.

Which airlines fly direct from Manaus to Panama City?

Copa, United and GOL Linhas Aéreas fly direct from Manaus to Panama City.

How many flights are there a week from Manaus to Panama City?

As of March 2026, there are 50 flights per week flying from Manaus to Panama City.

When is the cheapest time to fly from Manaus to Panama City?

The cheapest month to fly from Manaus to Panama City is usually March.

Which is the cheapest airport to fly into in Panama City?

If you're flying from Manaus Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from $714.

Which upcoming date is cheapest to fly from Manaus Airport to Panama City on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Manaus Airport to Panama City on Thursday, 26 March 2026.

Can I get a direct flight from Manaus Airport to Panama City?

Yes – the average flight time is 3 hours and 46 minutes.

How can I get the best flight deal from Manaus Airport to Panama City?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Panama City?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Panama City?

In March, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.

Which is the cheapest airline to fly from Manaus Airport to Panama City with?

Currently, Avianca and Copa offer the cheapest flight tickets to Panama City.

Travelling from Eduardo Gomes International Airport (MAO) to Panama City: what you need to know

The average length of a direct flight from Eduardo Gomes International Airport to Panama City is 3 hours 55 minutes.
The timezone in Panama City is UTC-5. The city is one hour behind Manaus, where Eduardo Gomes International Airport is located.
Eduardo Gomes International Airport (MAO) to Tocumen International Airport (PTY) is the most traveled route, with six weekly flights to pick from. You can fly from MAO to PTY at 03:35 with Copa Airlines.
Leave enough time to get on your MAO to Panama City flight. Generally, it's best to arrive at least two hours before international departures and an hour ahead for domestic flights.
If you're flying during a bank holiday or another peak period, give yourself more time. A good general rule is two hours before domestic flights and up to four hours before international departures. Queues at check-in and security will be longer.
Start your journey at MAO and fly nonstop to Tocumen International Airport (PTY). That's where you can expect to touch down when searching for Eduardo Gomes International Airport to Panama City tickets.
Book your seat with Copa Airlines. This well-known carrier offers direct flights from Eduardo Gomes International Airport to Panama City.
Finding a flight ticket from MAO to Panama City with a stopover is a breeze. Whether you're eager to snag a discounted fare or add a new city to your itinerary, just deselect 'Direct flights only' to view your options. A popular stop is El Dorado International Airport (BOG).
MAO is around 48 kilometres from central Manaus. If you're catching a cab, ride-sharing or driving from the centre, it'll take you 20 minutes or so to get there, depending on traffic conditions. If you're planning to take public transport, expect the journey time to be around 50 minutes.
Planning to catch an early flight from Eduardo Gomes International Airport to Panama City? Avoid the stress of rushing to the airport (and sneak in some extra precious sleep) by choosing one of these hotels near MAO:
76.84% of flights leaving from Eduardo Gomes International Airport reach their destination on time.

How to find the cheapest flights from Eduardo Gomes International Airport (MAO) to Panama City

The lowest price we've found for a one-way Eduardo Gomes International Airport to Panama City flight is $327. The cheapest price for a return flight is $714. Remember fares can change due to demand at the time of booking.
Get cheap flights from MAO to Panama City by booking four months ahead. Based on our research, that's the sweet spot for bagging a bargain.
Schedule your trip for August. That's the best month for scoring an epic deal on Eduardo Gomes International Airport to Panama City tickets. If you have flexibility with your dates, use the 'Whole month' tool to find the cheapest price across each month.
Picking up a cheap flight from MAO to Panama City couldn't be easier with Price Alerts. All you need to do is create one of these automatic notifications and we'll let you know when a deal gets even better.
Find an affordable flight from Eduardo Gomes International Airport to Panama City with the help of our filters. Choose your preferred times, airlines and number of stops, then sort the results by 'Cheapest' to see the best deals.

Airports in Panama City

Tocumen International Airport (PTY)

Tocumen International Airport (PTY) is around 21 kilometres from central Panama City. If you're catching a cab or a ride-share, the drive takes about 20 minutes.
It'll take around 1 hour 5 minutes if you're travelling by public transport.
Look into staying at a hotel close to PTY if you have a late flight from Eduardo Gomes International Airport to Panama City. Settle into one of these accommodation options and skip the long transfer:
Pick up a Tocumen International Airport rental car and discover Panama City and beyond with your own wheels. Avis, Dollar and MEX are popular providers you can book with here.
Booking your ride from Tocumen International Airport about three weeks in advance of your flight from MAO to Panama City can help you lock in the best possible rate.

Marcos A. Gelabert International Airport (PAC)

The centre of Panama City is about 2 kilometres from Marcos A. Gelabert International Airport (PAC). Once your flight from Eduardo Gomes International Airport to Panama City has hit the runway and you've made your way through the terminal, the drive should take about 5 minutes.
If you choose to travel on public transport, the journey will take you 25 minutes or so.
Hang the 'Do not disturb' sign on your door and rest at a hotel close to PAC. Here are a few options where you can kick back after your MAO to Panama City flight:
Forget about inconvenient public transport schedules or cab lines. Grab a Marcos A. Gelabert International Airport rental car and take your trip in whatever direction you choose. Check out the availability and rates from Thrifty, Avis and Alamo.
Avoid potential price surges. Reserving your ride three weeks ahead of your arrival at PAC will help you save.

Panama Pacifico Airport (BLB)

Panama Pacifico Airport (BLB) is about 16 kilometres from the centre of Panama City. It'll take you about 20 minutes to reach the city centre by cab or ride-share once you've stepped off your flight from Eduardo Gomes International Airport to Panama City.
If you don't want to travel into the centre, head for a hotel close to BLB. Settle in at one of these stays after your MAO to Panama City flight:
Whether you'd like a zippy compact for solo travel or a spacious SUV to transport your group, you'll find the perfect Panama Pacifico Airport rental car for your needs. Browse the range of wheels available here from names such as Sixt, Dollar and Thrifty.
About one week ahead of your flight from Eduardo Gomes International Airport to Panama City is the ideal time to book your vehicle from BLB. You're likely to snag a better deal or score some early bird savings.

Best time to go to Panama City

Before locking in your flights from Eduardo Gomes International Airport to Panama City, consider which time of year works best for you. Peak season in Panama City offers a bustling atmosphere and plenty of activities, while low season means you'll get cheaper hotel rates and smaller crowds.
The warmest month in Panama City is March, with temperatures ranging between 21ºC and 32ºC. Book your Eduardo Gomes International Airport to Panama City flight ticket then if that's your idea of comfortable weather.
If you like cooler conditions, search for a cheap ticket from MAO to Panama City in February when temperatures average between 22ºC and 31ºC.

More about Panama City

After booking your flight from Eduardo Gomes International Airport to Panama City, find a hotel that offers the right mix of comfort and location. Make one of these options your base for exploring Panama City:
Casco Viejo and Panama Canal Museum are a couple of top attractions to put on your Panama City to-do list. Keep the sightseeing going at Cinta Costera.

Explore more of Panama

Panama City is easy to fall in love with, but there are so many other corners of Panama you'll want to see. Around 322 kilometres west of Panama City, a trip to David will keep your itinerary packed. Start with popular sights like Parque Cervantes, Altos del Rio Park and Coquito Hills Park.
Santiago de Veraguas is another favourite destination in Panama and is around 193 kilometres south-west of Panama City. No trip is complete without a visit to Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios.